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Altoprev (lovastatina de liberación prolongada), Livalo (pitavastatina), Pravacol (pravastatina), Crestor (rosuvastatina) y Zocor (simvastatina). Al igual que otras estatinas, la pravastatina inhibe en forma competitiva a la La coadministración con fibratos (bezafibrato, gemfibrozilo), niacina, eritromicina. fluvastatina mg, lovastatina 40 mg, pravastatina. 40 mg . 3A4: ciclosporina, fibratos (gemfibrozil, bezafibrato, fenofibrato y ciprofibrato).

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Enhanced cholesterol reduction by simvastatin in diltiazem-treated patients. Acute renal failure with the combined use of rosuvastatin and fenofibrate. Rhabdomyolysis associated with atorvastatin combined with amiodarone and fluconazole.

Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion. Rhabdomyolysis resulting from pharmacologic interaction between erlotinib and simvastatin.

Irbesartan does not affect the pharmacokinetics of simvastatin in healthy subjects. Henao 1M. Rhabdomyolysis due to an uncommon interaction of ciprofloxacin with simvastatin. Effect of itraconazole on the pharmacokinetics of atorvastatin.

Concomitant administration of cholestyramine influences the absorption of troglitazone. Rhabdomyolysis due to probable interaction between simvastatin and ritonavir. FDA adverse event reports on statin-associated rhabdomyolysis.

Br Prravastatina Clin Pharmacol. Acute myopathy in a type 2 diabetic patient on combination pravastayina with metformin, fenofibrate and rosiglitazone. Experience shows that de-sensitization to allopurinol is a safe alternative when there is hypersensitivity and treatment with this drug is required.


Rifampin greatly reduces plasma simvastatin and simvastatin acid concentrations. Pharmacokinetic interactions between statins and fibrates.

Rhabdomyolysis secondary to interaction of fusidic acid and simvastatin. J Acquir Immune Defic Syndr.


Peces R, Pobes A. Pharmacokinetics of pravastatin in heart-transplant patients taking cyclosporin A.

Evaluation of a pharmacokinetic interaction between valsartan and simvastatin in healthy subjects. Pharmacokinetic pravaztatina of fluvastatin in patients chronically receiving digoxin. Efecto que no se observa para la pravastatina Reduced efficacy of rosuvastatin by St. A prospective study in renal transplant patients. A randomized, placebo-controlled trial to evaluate the efficacy, safety, and pharmacodynamic interaction of coadministered amlodipine and atorvastatin in patients bezaafibrato concomitant hypertension and dyslipidemia: Rhabdomyolysis with simvastatin and nefazodone.

The effect of a combination antacid preparation containing aluminium hydroxide and magnesium hydroxide on rosuvastatin pharmacokinetics. Rhabdomyolysis following co-prescription of fusidic acid and atorvastatin. Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: An outpatient drug de-sensitization protocol was initiated, starting with 5 mg, and with gradual dose increases every 4 to 5 days for 59 bezafinrato until the desired maintenance dose mg was reached.

bezafibrato: dosis, para que sirve, efectos secundarios

Grapefruit juice greatly g serum concentrations of lovastatin and lovastatin acid. Rhabdomyolysis in association with simvastatin and amiodarone. Eltrombopag increases plasma rosuvastatin exposure in healthy volunteers. Pharmacokinetic interaction between isradipine and lovastatin in normal, female and male volunteers.


Vademécum Académico de Medicamentos | AccessMedicina | McGraw-Hill Medical

Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes. Tophi were found in metacarpophalangeal joints and elbows. Cimetidine does not alter atorvastatina pharmacokinetics or LDL-cholesterol reduction. Of the interactions identified in patients on hypolipidemic drugs, Rhabdomyolysis and acute kidney injury secondary to concomitant use of fluvastatin and rapamycin in a renal transplant recipient.

Pharmacokinetic interactions between nelfinavir and 3-hydroxymethylglutaryl coenzyme A reductase inhibitors atorvastatin and simvastatin. Rhabdomyolysis associated with concomitant use of atorvastatin and cyclosporine.

Finally, a method was used to assess the clinical relevance of the interaction, based on the likelihood of occurrence and the severity of the effect of the interaction. Pharmacokinetic interaction between ezetimibe and lovastatin in healthy volunteers. Oral anticoagulant drug interactions with statins: Curr Med Res Opin.